INTRATOL
INTRA LIFE: Empowering Patients, Transforming Hyponatremia Care
Hyponatremia, the most common electrolyte disorder, can have severe implications on one's health and well-being. At INTRA LIFE, we are dedicated to providing advanced solutions for the effective management of hyponatremia, ensuring improved outcomes and enhanced quality of life for our patients. Our expertise lies in the use of IntraTol Tolvaptan Tablets 15mg, a breakthrough medication that has revolutionized the treatment of this condition.
Hyponatremia is a medical condition characterized by low levels of sodium in the blood. It can be caused by various factors, such as the syndrome of inappropriate antidiuretic hormone secretion (SIADH), heart failure, and autosomal dominant polycystic kidney disease. SIADH alone accounts for a staggering 62% of hyponatremia cases, significantly increasing the risk of morbidity and mortality.
There are three main types of hyponatremia:
Euvolemic hyponatremia : is the most common type. It occurs when the body has the right amount of water, but the sodium level is too low. This can be caused by a variety of factors, including syndrome of inappropriate antidiuretic hormone (SIADH), heart failure, and liver disease.
Hypovolemic hyponatremia : occurs when the body has too little water. This can be caused by dehydration, diarrhea, and vomiting.
Hypervolemic hyponatremia : occurs when the body has too much water. This can be caused by kidney disease, heart failure, and certain medications.
The symptoms of hyponatremia can vary depending on the severity of the condition. Mild hyponatremia may not cause any symptoms. However, as the condition worsens, symptoms can include:
Headache
Nausea
Vomiting
Confusion
Seizures
Coma
IntraTol Tolvaptan Tablets 15mg: The Ultimate Solution
Our flagship product, IntraTol Tolvaptan Tablets 15mg, is a game-changer in hyponatremia management. It has been specifically designed to address the underlying causes of this condition and provide effective relief. When administered to patients with euvolemic hyponatremia, including those with SIADH, it rapidly increases serum sodium levels by an average of 9.9+4.5 mmol within 24 hours.
Advantages of IntraTol Tolvaptan Tablets 15mg
1. Improved Mental and Physical Scores: In addition to raising serum sodium levels, IntraTol Tolvaptan Tablets 15mg significantly improve mental and physical well-being. Patients experience enhanced cognitive function and physical performance without the occurrence of neurological events.
2. Effective for Elderly Patients: Hyponatremia is particularly prevalent among elderly patients, with an average occurrence rate of approximately 25.98%. IntraTol Tolvaptan Tablets 15mg offer a safe and efficient treatment option for this vulnerable population.
3. Conditions Addressed: IntraTol Tolvaptan Tablets 15mg
Why Choose IntraTol Tolvaptan Tablets 15mg?
Unparalleled Efficacy: IntraTol Tolvaptan Tablets 15mg is a highly potent and effective medication specifically designed to address hyponatremia. By targeting the underlying cause of the condition, our tablets help restore sodium balance in the body, thereby improving overall health and well-being.
Expertly Formulated: Our tablets are meticulously formulated with the utmost care and precision, ensuring optimal potency and purity. Backed by extensive research and clinical trials, IntraTol Tolvaptan Tablets 15mg deliver exceptional results, providing patients with the relief they need.
Personalized Treatment: We understand that every patient's journey with hyponatremia is unique. That's why we prioritize personalized care and treatment plans. Our team of experienced healthcare professionals works closely with patients to develop tailored strategies, taking into account individual needs, medical history, and lifestyle factors.
Comprehensive Support: At INTRA LIFE, we believe in going beyond just medication. We provide comprehensive support to our patients, offering educational resources, lifestyle guidance, and ongoing monitoring to ensure they receive the best possible care. Our dedicated team is always available to address any concerns and answer questions throughout the treatment process.
Commitment to Safety: Patient safety is our top priority. IntraTol Tolvaptan Tablets 15mg undergo rigorous quality control measures and adhere to stringent safety standards. We are committed to ensuring that our medication is safe, reliable, and well-tolerated, giving patients peace of mind as they embark on their journey towards recovery.
Enhanced Convenience: With IntraTol Tolvaptan Tablets 15mg, we aim to make treatment as convenient as possible. Our tablets are easy to administer, allowing patients to take their medication at home without the need for complicated procedures or frequent hospital visits. This empowers patients to take control of their treatment while minimizing disruptions to their daily lives.
For Whom is IntraTol Tolvaptan Tablets 15mg Suitable?
Patients with Chronic Hyponatremia: IntraTol Tolvaptan Tablets 15mg are suitable for individuals diagnosed with chronic hyponatremia, a condition where low sodium levels persist over an extended period. Our medication offers long-term management and helps prevent complications associated with chronic hyponatremia.
Hospitalized Patients with Hyponatremia: Hyponatremia can occur in hospitalized patients due to various factors such as fluid imbalances or underlying medical conditions. IntraTol Tolvaptan Tablets 15mg can be prescribed to these patients to restore sodium levels and support their recovery.
Adults with Euvolemic or Hypervolemic Hyponatremia: IntraTol Tolvaptan Tablets 15mg are indicated for adults with euvolemic or hypervolemic hyponatremia, conditions where sodium levels are low despite normal or increased fluid levels. Our medication helps normalize sodium levels, promoting overall health and well-being.
Patients Under Medical Supervision: IntraTol Tolvaptan Tablets 15 mg should be taken under medical supervision. Our healthcare professionals closely monitor patients to ensure the safe and effective use of the medication and adjust the dosage as needed based on individual response and sodium level fluctuations.
Qualitative and Quantitative composition of IntraTol Tolvaptan Tablets 15mg:
Qualitative CompositionTolvaptan
Quantitative Composition
Each tablet contains 15 mg of tolvaptan.
Inactive Ingredients
Lactose monohydrate
Microcrystalline cellulose
Sodium starch glycolate
Magnesium stearate
Hypromellose
Titanium dioxide
Macrogol 4000
Talc
The recommended dosage of IntraTol Tolvaptan Tablets 15mg to 60mg per day. Titrate to 30 mg once daily, after at Dosage least 24 hours, up to a maximum of 60 mg once daily. The dosage may be increased to 30 mg once daily after at least 24 hours, if needed. The maximum daily dosage is 60 mg.
IntraTol Tolvaptan Tablets 15mg can be taken with or without food. It is important to take IntraTol Tolvaptan Tablets 15mg at the same time each day.
IntraTol Tolvaptan Tablets 15 mg should be stored at room temperature (15-30 degrees Celsius) in a dry place. Keep out of reach of children and pets.
Unused or expired IntraTol Tolvaptan Tablets 15mg should be disposed of in accordance with local regulations.
If you miss a dose of IntraTol Tolvaptan Tablets 15mg, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of IntraTol Tolvaptan Tablets 15mg at the same time.
If you take too much IntraTol Tolvaptan Tablets 15mg, call your doctor or poison control center immediately. Symptoms of an overdose may include headache, dizziness, fatigue, nausea, vomiting, and diarrhea.
The most common side effects of IntraTol Tolvaptan Tablets 15mg are headache, dizziness, fatigue, nausea, vomiting, and diarrhea. These side effects are usually mild and go away on their own.
IntraTol Tolvaptan Tablets 15mg can cause serious side effects, including:
Hypovolemia (low blood volume)
Hyponatremia (low sodium levels in the blood)
Clinical Particulars
The clinical particulars of IntraTol Tolvaptan Tablets 15mg are as follows:Indication: IntraTol Tolvaptan Tablets 15mg is indicated for the treatment of hyponatremia in adults. Dosage and Administration: The recommended dosage of IntraTol Tolvaptan Tablets 15mg is 15 mg once daily. The dosage may be increased to 30 mg once daily after at least 24 hours, if needed. The maximum daily dosage is 60 mg.
Contraindications: IntraTol Tolvaptan Tablets 15mg is contraindicated in patients with:
Hypervolemia
Hypovolemia
Severe liver impairment
Severe kidney impairment
Pregnancy
Breastfeeding
Warnings and Precautions: IntraTol Tolvaptan Tablets 15mg should be used with caution in patients with:
Heart failure
Cirrhosis
Hypotension
Dehydration
Diabetes
History of seizures
History of kidney stones
Adverse Reactions: The most common side effects of IntraTol Tolvaptan Tablets 15mg are headache, dizziness, fatigue, nausea, vomiting, and diarrhea. These side effects are usually mild and go away on their own.
Drug Interactions: IntraTol Tolvaptan Tablets 15mg may interact with other medications, including diuretics, lithium, and certain antibiotics.
Overdose: Symptoms of an overdose of IntraTol Tolvaptan Tablets 15mg may include headache, dizziness, fatigue, nausea, vomiting, and diarrhea.
Storage: IntraTol Tolvaptan Tablets 15mg should be stored at room temperature (15-30 degrees Celsius) in a dry place. Keep out of reach of children and pets.
Disposal: Unused or expired IntraTol Tolvaptan Tablets 15mg should be disposed of in accordance with local regulations.
In addition to these clinical particulars, it is important to note that IntraTol Tolvaptan Tablets 15mg can cause serious side effects, including:Hypovolemia (low blood volume)
Hyponatremia (low sodium levels in the blood)
Dehydration
Kidney problems
Liver problems
Allergic reactions
Pharmacological properties
Mechanism of Action: IntraTol Tolvaptan Tablets 15mg is a selective vasopressin V2 receptor antagonist. Vasopressin is a hormone that helps the body retain water. By blocking the V2 receptors, IntraTol Tolvaptan Tablets 15mg causes the body to excrete more water, which can help to raise sodium levels in the blood.
Pharmacokinetics: IntraTol Tolvaptan Tablets 15mg is rapidly absorbed from the gut and reaches peak plasma concentrations within 1-2 hours. It is metabolized in the liver and excreted in the urine.
Pharmacodynamics: IntraTol Tolvaptan Tablets 15mg is a potent and selective V2 receptor antagonist. It has been shown to be effective in raising sodium levels in the blood in patients with hyponatremia.
Clinical Studies: IntraTol Tolvaptan Tablets 15mg has been studied in a number of clinical trials. In one study, IntraTol Tolvaptan Tablets 15mg was shown to increase serum sodium levels by an average of 9.9 mmol/L within 24 hours in patients with hyponatremia.
Adverse Reactions: The most common side effects of IntraTol Tolvaptan Tablets 15mg are headache, dizziness, fatigue, nausea, vomiting, and diarrhea. These side effects are usually mild and go away on their own.
Drug Interactions: IntraTol Tolvaptan Tablets 15mg may interact with other medications, including diuretics, lithium, and certain antibiotics.
Overdose: Symptoms of an overdose of IntraTol Tolvaptan Tablets 15mg may include headache, dizziness, fatigue, nausea, vomiting, and diarrhea.
Storage: IntraTol Tolvaptan Tablets 15mg should be stored at room temperature (15-30 degrees Celsius) in a dry place. Keep out of reach of children and pets.
Disposal: Unused or expired IntraTol Tolvaptan Tablets 15mg should be disposed of in accordance with local regulations.
Nonclinical properties
Toxicology: IntraTol Tolvaptan Tablets 15mg has been shown to be safe in animal studies. The most common side effects observed in animal studies were similar to those observed in human studies, including headache, dizziness, fatigue, nausea, vomiting, and diarrhea.
Carcinogenesis: IntraTol Tolvaptan Tablets 15mg was not found to be carcinogenic in animal studies.
Mutagenesis: IntraTol Tolvaptan Tablets 15mg was not found to be mutagenic in animal studies.
Reproductive Toxicity: IntraTol Tolvaptan Tablets 15mg was shown to be embryotoxic and fetotoxic in animal studies. It is not recommended for use in pregnant women or women who are breastfeeding.
Pharmacokinetics: The pharmacokinetics of IntraTol Tolvaptan Tablets 15mg in animals are similar to those in humans.
Pharmacodynamics: The pharmacodynamics of IntraTol Tolvaptan Tablets 15mg in animals are similar to those in humans.
Pharmaceutical Particulars
Dosage: The recommended dosage of IntraTol Tolvaptan Tablets 15mg is 15 mg once daily. The dosage may be increased to 30 mg once daily after at least 24 hours, if needed. The maximum daily dosage is 60 mg.
Route of Administration: IntraTol Tolvaptan Tablets 15mg are taken orally.
Storage: IntraTol Tolvaptan Tablets 15mg should be stored at room temperature (15-30 degrees Celsius) in a dry place. Keep out of reach of children and pets.
Disposal: Unused or expired IntraTol Tolvaptan Tablets 15mg should be disposed of in accordance with local regulations.
Here are some of the other pharmaceutical particulars of IntraTol Tolvaptan Tablets 15mg:
Active Ingredient: Tolvaptan
Inactive Ingredients: Lactose monohydrate, microcrystalline cellulose, sodium starch glycolate, magnesium stearate, hypromellose, titanium dioxide, macrogol 4000, talc
Packaging: IntraTol Tolvaptan Tablets 15mg are available in bottles of 30 tablets
Marketing Authorization Holder: IntraLife Pharmaceuticals Pvt. Ltd.
Country of Manufacture: India
Patient Counselling Information
Take IntraTol Tolvaptan Tablets 15mg exactly as prescribed by your doctor. Do not take more or less of the medication, or take it more often than prescribed.
You can take IntraTol Tolvaptan Tablets 15mg with or without food.
It is important to drink plenty of fluids while taking IntraTol Tolvaptan Tablets 15mg. This will help to prevent dehydration.
If you miss a dose of IntraTol Tolvaptan Tablets 15mg, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of IntraTol Tolvaptan Tablets 15mg at the same time.
If you take too much IntraTol Tolvaptan Tablets 15mg, call your doctor or poison control center immediately. Symptoms of an overdose may include headache, dizziness, fatigue, nausea, vomiting, and diarrhea.
Tell your doctor about all of your current medications, including prescription and over-the-counter medications, vitamins, and herbal supplements. IntraTol Tolvaptan Tablets 15mg may interact with other medications.
Tell your doctor if you are pregnant or breastfeeding. IntraTol Tolvaptan Tablets 15mg is not recommended for use in pregnant women or women who are breastfeeding.
Store IntraTol Tolvaptan Tablets 15mg at room temperature (15-30 degrees Celsius) in a dry place. Keep out of reach of children and pets.
Dispose of Unused or expired IntraTol Tolvaptan Tablets 15mg in accordance with local regulations.
INTRA LIFE is committed to empowering patients and transforming hyponatremia care. With IntraTol Tolvaptan Tablets 15mg, we offer an ultimate solution that effectively restores sodium balance, alleviates symptoms, and improves the quality of life for individuals with hyponatremia.